CA5A (англ.Carbonic anhydrase 5A) – білок, який кодується однойменним геном, розташованим у людей на 16-й хромосомі.[5] Довжина поліпептидного ланцюга білка становить 305 амінокислот, а молекулярна маса — 34 750[6].
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Nagao Y., Batanian J.R., Clemente M.F., Sly W.S. (1995). Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p. Genomics. 28: 477—484. PMID7490083DOI:10.1006/geno.1995.1177
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14: 2121—2127. 2004. PMID15489334DOI:10.1101/gr.2596504
Temperini C., Scozzafava A., Vullo D., Supuran C.T. (2006). Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme. Chemistry. 12: 7057—7066. PMID16807956DOI:10.1002/chem.200600159
Temperini C., Scozzafava A., Vullo D., Supuran C.T. (2006). Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design. J. Med. Chem. 49: 3019—3027. PMID16686544DOI:10.1021/jm0603320
Temperini C., Innocenti A., Scozzafava A., Mastrolorenzo A., Supuran C.T. (2007). Carbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV. Bioorg. Med. Chem. Lett. 17: 628—635. PMID17127057DOI:10.1016/j.bmcl.2006.11.027